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Key Benefits

Suggested Use

Important Notices

Methylcobalamin is essential for the body to recycle homocysteine and to form the internal methyl donors involved in cardiovascular function, sleep, blood cell formation, and nerve function.* Most vitamin B12 supplements contain cyanocobalamin; however, the liver must first "detoxify" the cyanide molecule in cyanocobalamin and then attach a methyl group to form methylcobalamin.

Although research shows the quantity of cobalamin detected following an oral dose of methylcobalamin is similar to the amount following administration of cyanocobalamin, significantly more cobalamin accumulates in liver tissue following administration of methylcobalamin. And the urinary excretion of methylcobalamin is about one-third that of a similar dose of cyanocobalamin, indicating substantially greater tissue retention of the former.*

This product has been third-party tested and certified to verify what's in the package matches what's on the label and to confirm it contains no unsafe levels of contaminants, such as heavy metals, pesticides, and microorganisms.

Thorne

Vitamin B12 - 60 Servings

Many vitamin B12 supplements contain cyanocobalamin as the active ingredient, which the liver must first "detoxify" and modify to form methylcobalamin – an active form of vitamin B12 that is essential for processes involved in cardiac function, sleep, blood cell formation, and nerve function.* Thorne's Vitamin B12, as Methylcobalamin, provides vitamin B12 in its already biologically active and tissue-ready form.* Clinical evidence indicates that the body uses methylcobalamin more efficiently than cyanocobalamin.* Methylcobalamin helps maintain normal circadian rhythms to promote normal sleep and supports healthy methylation processes in the body.*

 

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HIPAA Compliant · CLIA Certified · CAP Accredited · Quest Diagnostics Partner · HSA/FSA Eligible

Sign up for the latest in personalized health, insights, and updates.

© 2026 Hundred. All rights reserved

2 Embarcadero Center, Floor 8, San Francisco, CA 94111